We introduce a novel self-supervised pretext task for learning representations from audio-visual content.

While these approaches learn high-quality representations for downstream tasks such as action recognition, their training objectives disregard spatial cues naturally occurring in audio and visual signals.

Recent advances in image-level self-supervised learning (SSL) have made significant progress, yet learning dense representations for patches remains challenging. Mainstream methods encounter an over-dispersion phenomenon that patches from the same instance/category scatter, harming downstream performance on dense tasks. This work reveals that image-level SSL avoids over-dispersion by involving implicit semantic concentration. Specifically, the non-strict spatial alignment ensures intra-instance consistency, while shared patterns, i.e., similar parts of within-class instances in the input space, ensure inter-image consistency. Unfortunately, these approaches are infeasible for dense SSL due to their spatial sensitivity and complicated scene-centric data. These observations motivate us to explore explicit semantic concentration for dense SSL. First, to break the strict spatial alignment, we propose to distill the patch correspondences. Facing noisy and imbalanced pseudo labels, we propose a noise-tolerant ranking loss. The core idea is extending the Average Precision (AP) loss to continuous targets, such that its decision-agnostic and adaptive focusing properties prevent the student model from being misled. Second, to discriminate the shared patterns from complicated scenes, we propose the object-aware filter to map the output space to an object-based space. Specifically, patches are represented by learnable prototypes of objects via cross-attention. Last but not least, empirical studies across various tasks soundly support the effectiveness of our method. Code is available in https://github.com/KID-7391/CoTAP.

Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial alignment and complex inter-channel relationships. Generative modeling of such data requires jointly capturing intra- and inter-channel structure, while also generalizing across arbitrary combinations of observed and missing channels for practical application. Existing diffusion-based models generally assume low-dimensional inputs (e.g., RGB images) and rely on simple conditioning mechanisms that break spatial correspondence and ignore inter-channel dependencies. This work proposes a unified diffusion framework for controllable generation over structured and spatial biological data. Our model contains two key innovations: (1) a hierarchical feature injection mechanism that enables multi-resolution conditioning on spatially aligned channels, and (2) a combination of latent-space and output-space channel-wise attention to capture inter-channel relationships. To support flexible conditioning and generalization to arbitrary subsets of observed channels, we train the model using a random masking strategy, enabling it to reconstruct missing channels from any combination of inputs. We demonstrate state-of-the-art performance across both spatial and non-spatial prediction tasks, including protein imputation in IMC and gene-to-protein prediction in single-cell datasets, and show strong generalization to unseen conditional configurations.

What representation do deep neural networks learn? How similar are images to each other for neural networks? Despite the overwhelming success of deep learning methods key questions about their internal workings still remain largely unanswered, due to their internal high dimensionality and complexity. To address this, one approach is to measure the similarity of activation responses to various inputs.Representational Similarity Matrices (RSMs) distill this similarity into scalar values for each input pair.These matrices encapsulate the entire similarity structure of a system, indicating which input lead to similar responses.While the similarity between images is ambiguous, we argue that the spatial location of semantic objects does neither influence human perception nor deep learning classifiers. Thus this should be reflected in the definition of similarity between image responses for computer vision systems.

Existing multimodal UAV object detection methods often overlook the impact of semantic gaps between modalities, which makes it difficult to achieve accurate semantic and spatial alignments, limiting detection performance. To address this problem, we propose a Large Language Model (LLM) guided Progressive feature Alignment Network called LPANet, which leverages the semantic features extracted from a large language model to guide the progressive semantic and spatial alignment between modalities for multimodal UAV object detection. To employ the powerful semantic representation of LLM, we generate the fine-grained text descriptions of each object category by ChatGPT and then extract the semantic features using the large language model MPNet. Based on the semantic features, we guide the semantic and spatial alignments in a progressive manner as follows. First, we design the Semantic Alignment Module (SAM) to pull the semantic features and multimodal visual features of each object closer, alleviating the semantic differences of objects between modalities. Second, we design the Explicit Spatial alignment Module (ESM) by integrating the semantic relations into the estimation of feature-level offsets, alleviating the coarse spatial misalignment between modalities. Finally, we design the Implicit Spatial alignment Module (ISM), which leverages the cross-modal correlations to aggregate key features from neighboring regions to achieve implicit spatial alignment. Comprehensive experiments on two public multimodal UAV object detection datasets demonstrate that our approach outperforms state-of-the-art multimodal UAV object detectors.